CASE II
PATIENT DATA BASE
A. Patient Description:
- Name : ZEH
- Age : 35 years
- DOA : 21/09//07
- Gender : Female
- Ward : ICU/B7
B. Chief complaint:
Cough, SOB, fever – 3/7
C. History of present illness:
Miss. ZEH is a 35 year-old woman brought to ICU on 21st of Sept 2007 from BM hospital because complaining of cough, SOB and fever for past few days. She was admitted to BM hospital on the morning of 21st of Sept and was diagnosed as severe Community Acquired Pneumonia (CAP). She was then sent to Hospital Pulau Pinang on same day in the afternoon for intubation due to compensated metabolic acidosis. In Hospital Pulau Pinang, she was diagnosed as severe CAP and secondary sepsis.
D. Past Medical History
- Hypertension
- DM
E. Family/Social History
· Not known family history of any medical illness.
· Not married.
· Non-smoker. Alcohol intake?
F. Allergies
NKDA.
G. Past Medication History
Could not be obtained.
H. Review of System
· O/E – alert, tachypneic, obese
· BP – 110/70
· P – 150
· T – 37.5
· SPO2 – 66 – 70%
· CXR – Bilateral opacity
· Lungs – fairly clear
I. Laboratory Investigation
DATE | 21/9 | 22/9 | 23/9 | 24/9 | 25/9 | |
BLOOD CHEMISTRY | NORMAL | |||||
Na+ | 135-145 mmol/L | 131 | 137 | 145 | 149 | 141 |
K+ | 3.5-5.0 mmol/L | 3.9 | 4.6 | 3.5 | 3.7 | 4.0 |
BUN | 1.7-8.3 mmol/L | 9.4 | 7.7 | 8.0 | 9.5 | 9.5 |
Creatinine | 57-130 mmol/L | 79 | 77 | 67 | 56 | 53 |
Cl | 96-106 mmol/L | 100 | 114 | 114 | 116 | 113 |
Cr Cl | 75-125 ml/min | 124 | 128 | 146 | 176 | 185 |
Mg+ | 0.8-1.0 mmol/L | 0.7 | 1.22 | |||
Ca2+ | 2.1-2.55 mmol/L | 1.82 | 1.79 | |||
PO4 | 0.89-1.40 mmol/L | 1.24 | ||||
HEMATOLOGY | ||||||
Hct | 36-46% | 33.3 | 32.1 | 30.5 | 33.4 | 31.6 |
HgB | 12-16g/dl | 11.6 | 10.6 | 9.9 | 10.8 | 10.1 |
WBC | 4.5-11 x109/L | 11.7 | 11.0 | 10.4 | 11.4 | 10.6 |
RBC | 4.7-6.1 x 1012/L | 3.5 | 3.8 | 3.5 | ||
PLT | 130-400 x103/mml | 98 | 160 | 191 | 266 | 270 |
LYM | 16-45% | |||||
NEUT | 45-74% | |||||
LIVER FT | ||||||
PT | 10.7-13.7 sec | 13.1 | 14.2 | 13.6 | 13.0 | 13.4 |
INR | 1.0-1.24 | 1.1 | 1.2 | 1.1 | 1.1 | 1.1 |
APPT | 25-40 sec | 28.8 | 29.2 | 24.3 | 21.5 | 23.6 |
CARDIAC ENZYMES | ||||||
AST | 1-37U/L | 148 | 1078 | 661 | 426 | |
LDH | 50-150U/L | 659 | 1117 | 844 | 969 | |
CK | 0-130U/L | 40 | 103 | 73 | 58 | |
ABG | ||||||
pH | 7.35-7.45 | 7.36 | 7.38 | 7.4 | 7.42 | 7.46 |
PO2 | 75-100 mmHg | 56 | 125 | 131 | 109 | 94 |
PCO2 | 35-45 mmHg | 26.6 | 35 | 39 | 41 | 37 |
HCO3 | 24-28 mmol/L | 9.0 | 21.8 | 24.2 | 26.6 | 26.9 |
SPO2 | 90-95% | 68% | 99% | 98% | 98% | |
Drug Name / Route | Dose / Frequency | Duration | Indication/Safety/Efficacy |
Start-Stop Date | |||
I.V Ranitidine 50mg | TDS | 21/9 - | |
I.V Ceftriaxone 2g | BD | 21/9 - | |
I.V Azithromycin 500mg | OD | 21/9 - | |
I.V CaCl2 1g | TDS | 21/9 – 24/9 | |
I.V MgSO4 20mmol | STAT & OD | 21/9 – 24/9 | |
I.V Calcium Gluconate 10mmol | STAT & OD | 21/9 – 24/9 | |
I.V Cloxacillin 2g | QID | 22/9 - |
Date | 21/907 | 22/9/07 | 23/9/07 | 24/9/07 | 25/907 | 26/907 | |
General | Mixed metabolic acidosis and respiratory alkalosis. Severe CAP RBS 20.7 mmol/L | UO 30-60ml/hr RBS 14.0 mmol/L Still malaenic stool Fibrinogen 137.9 mg/dL D-dimer >0.2 mg/dL | UO 70ml/hr Fibrinogen 137.9 D-dimer >0.2 Urine C & S no growth RBS 10.1 mmol/L | Mycoplasma serology borderline positive. RBS 4.7 Fibrinogen 149.1 D-dimer >0.2 | RBS 12.1 UO 70-80 ml/hr | RBS 3.8 UO 80-100 ml/hr | |
Vital signs | BP | 110/70 | 109/63 | 127/68 | 129/72 | 121/82 | 110/86 |
ABP | |||||||
PR | 150 | 133 | 107 | 95 | 92 | 102 | |
RR | |||||||
T | 37.5 | Spiking | 37.5 | Afebrile | 37 | 37 | |
CVP | 17 | 15 | 15 | 15 | |||
O2Sat | |||||||
CVS | ECG – sinus tachycardia | ||||||
Plan/Action Taken | Intubated. I.V Ranitidine 50mg TDS I.V Ceftriaxone 2g BD I.V Azithromycin 500mg OD I.V CaCl2 1g TDS I.V MgSO4 20mmol Stat & OD I.V Calcium Gluconate10mmol Stat & OD Insulin sliding scale Fluid resuscitation I.V Furosemide 10mg/hr | I.V Cloxacillin 2g QID KIV S/C Heparin 5000 U BD. I.V Tifacogin 14ml/hr for 96 hours via central line | Continue therapy | Continue therapy | Change I.V Ranitidine to 300mg ON | Off Insulin – start S/C insulin Completed I.V Tifacogin infusion Discharged to ward on 27/3. |
Daily Progress Report
MICROBIOLOGY TESTS
Source | Date | Results | Sensitive to | Resistant to |
Blood | 24/9/07 | Mycoplasma serology borderline positive. | - | - |
K. Diagnoses/Provisional Dx/Acute/Chronic Medical Problems:
1) Severe CAP – viral pneumonia?
- Atypical pneumonia?
1) Sepsis secondary to CAP
2) DM